Medical Illustration WIP: Bone Resorption by Osteoclasts

Please pardon my lack of posting in these past few weeks. Work temporarily took over! Let's get back to these step by steps shall we?


Below, I depict an osteoclast moving across the bone matrix and resorbing bone. Osteoclasts release digestive enzymes that break down the bone underneath.

 I almost always start with a sketch which I eventually colorize to complement to overall color of the piece.

I almost always start with a sketch which I eventually colorize to complement to overall color of the piece.

Next, I use big brushes to start indicating form. I used the emboss feature and a textured brush to create the subtle, raised appearance in the surrounding matrix. 

 New: Color and basic shadows. I added a subtle gradient to the background as well. 

New: Color and basic shadows. I added a subtle gradient to the background as well. 

Below I began adding highlighted regions. I also used a textured brush to create the look of chewed up/dissolved bone.

 New: Increased texture in the furrow, highlights

New: Increased texture in the furrow, highlights

If you compare the image below to the one above it, you'll notice that the one below is much warmer. When turning my layers on and off to create these step-by-steps, I must have mistakenly turned off the adjustment layer that colorized the sketch!

Below, I have sharpened the highlights and made them just a little more pronounced. I also added detail to make the osteoclast fringes look more embedded in the matrix.

 New: Sharpened highlights, detail along the Osteoclast (blue) fringes.

New: Sharpened highlights, detail along the Osteoclast (blue) fringes.

Below is the final illustration, with labels, as it appears in the poster. I added the text and arrow in Adobe InDesign.

figure_05e_fatunmbi.png

That's it for this week! Thanks for looking!